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cxc chemokine receptor type 1  (MedChemExpress)


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    Structured Review

    MedChemExpress cxc chemokine receptor type 1
    Cxc Chemokine Receptor Type 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cxc+chemokine+receptor+type+1/CD45%2C+Human/pmc07196669-70-17-31
    Average 94 stars, based on 6 article reviews
    cxc chemokine receptor type 1 - by Bioz Stars, 2026-09
    94/100 stars

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    Incubation:

    Article Title: 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) Mitigates Monosodium Urate (MSU)-Induced Acute Gouty Inflammation in BALB/c Mice
    Article Snippet: To prepare the supernatant to be placed in the lower chamber, 2 × 10 5 of THP-1 cells were treated with MSU crystals (200 μg/ml) for 24 h, with or without PLAG, and then the cells were centrifuged to obtain only the supernatant, which was then placed in the lower chambers and the 5-μm-pore transmigration chamber (Corning, NY, USA) was placed on top. .. Next, a selective CXCR2 antagonist (SB225002, at 2, 10, or 40 μM; Sigma, USA), an inhibitor of CXC chemokine receptor type 1 (CXCR1, CXCR2) (reparixin, at 2, 10, or 40 μM; Medchem Express, NJ, USA), or an IL-1 receptor antagonist (IL-1RA) (2, 10, or 40 ng/ml; Peprotech, NJ, USA) were treated to differentiated HL-60 (dHL-60, 2 × 10 5 cells), which mimics neutrophils. dHL-60 cells were placed on the upper chamber in 200 μl of serum-free RPMI 1640 medium and incubated for 24 h at 37°C. ..



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